3HSV

Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx-MacroH2ASBCpep2

3HSV の概要

• エントリーDOI: 10.2210/pdb3hsv/pdb
• 関連するPDBエントリー: 3HQI 3HQL 3HQM 3HTM 3HU6 3HVE
• 分子名称: Speckle-type POZ protein, Core histone macro-H2A.1, ZINC ION, ... (5 entities in total)
• 機能のキーワード: ubiquitin, e3, spop, macroh2a, nucleus, ubl conjugation pathway, alternative splicing, chromatin regulator, chromosomal protein, dna-binding, isopeptide bond, methylation, nucleosome core, phosphoprotein, ubl conjugation, ligase, protein binding
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 34800.75

構造登録者

Zhuang, M.,Schulman, B.A.,Miller, D. (登録日: 2009-06-10, 公開日: 2009-10-20, 最終更新日: 2023-09-06)

• 主引用文献: Zhuang, M.,Calabrese, M.F.,Liu, J.,Waddell, M.B.,Nourse, A.,Hammel, M.,Miller, D.J.,Walden, H.,Duda, D.M.,Seyedin, S.N.,Hoggard, T.,Harper, J.W.,White, K.P.,Schulman, B.A.; Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.; Mol.Cell, 36:39-50, 2009; PubMed: 19818708; DOI: 10.1016/j.molcel.2009.09.022

実験手法

X-RAY DIFFRACTION (1.43 Å)