3HSV
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx-MacroH2ASBCpep2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Speckle-type POZ protein | polymer | 145 | 16485.9 | 2 | UniProt (O43791) Pfam (PF22486) UniProt (by SIFTS) (Q5NVK7) In PDB | Homo sapiens (Human) | HIB homolog 1,Roadkill homolog 1 |
| 2 | M | Core histone macro-H2A.1 | polymer | 16 | 1536.6 | 1 | UniProt (O75367) In PDB | Homo sapiens (Human) | mH2A1,Histone H2A.y,H2A/y,Medulloblastoma antigen MU-MB-50.205 |
| 3 | A, B, M | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 4 | B | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | water | water | 18.0 | 400 | Chemie (HOH) |
Sequence modifications
A, B: 28 - 166 (UniProt: O43791)
M: 170 - 185 (UniProt: O75367)
| PDB | External Database | Details |
|---|---|---|
| Gly 22 | - | expression tag |
| Ser 23 | - | expression tag |
| Gly 24 | - | expression tag |
| Gly 25 | - | expression tag |
| Ser 26 | - | expression tag |
| Gly 27 | - | expression tag |
| Gly 140 | Asp 140 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ace 170 | Ala 171 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 34508.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 292.3 | |
| All* | Total formula weight | 34800.7 |
