3HQO
Crystal structures of Leishmania mexicana pyruvate kinase (LmPYK) in complex with ATP and Oxalate
Summary for 3HQO
Entry DOI | 10.2210/pdb3hqo/pdb |
Related | 1PKL 3E0V 3E0W 3HQN 3HQP 3HQQ |
Descriptor | Pyruvate kinase, MAGNESIUM ION, POTASSIUM ION, ... (5 entities in total) |
Functional Keywords | tim barrel, r-state enzyme, allosteric enzyme, glycolysis, kinase, magnesium, metal-binding, pyruvate, transferase |
Biological source | Leishmania mexicana |
Total number of polymer chains | 4 |
Total formula weight | 220554.76 |
Authors | Morgan, H.P.,Walkinshaw, M.D. (deposition date: 2009-06-08, release date: 2010-02-16, Last modification date: 2023-11-01) |
Primary citation | Morgan, H.P.,McNae, I.W.,Nowicki, M.W.,Hannaert, V.,Michels, P.A.M.,Fothergill-Gilmore, L.A.,Walkinshaw, M.D. The allosteric mechanism of pryuvate kinase from Leishmania mexicana: a rock and lock model J.Biol.Chem., 285:12892-12898, 2010 Cited by PubMed: 20123988DOI: 10.1074/jbc.M109.079905 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
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