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3HLF

Simvastatin Synthase (LovD), from Aspergillus terreus, S5 mutant, S76A mutant, complex with simvastatin

Summary for 3HLF
Entry DOI10.2210/pdb3hlf/pdb
Related3HLE
DescriptorTransesterase, Simvastatin acid (3 entities in total)
Functional Keywordsalpha/beta hydrolase fold, transferase
Biological sourceAspergillus terreus
Total number of polymer chains1
Total formula weight48584.24
Authors
Sawaya, M.R.,Yeates, T.O.,Pashkov, I.,Gao, X.,Tang, Y. (deposition date: 2009-05-27, release date: 2009-10-27, Last modification date: 2023-09-06)
Primary citationGao, X.,Xie, X.,Pashkov, I.,Sawaya, M.R.,Laidman, J.,Zhang, W.,Cacho, R.,Yeates, T.O.,Tang, Y.
Directed evolution and structural characterization of a simvastatin synthase
Chem.Biol., 16:1064-1074, 2009
Cited by
PubMed: 19875080
DOI: 10.1016/j.chembiol.2009.09.017
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

217705

數據於2024-03-27公開中

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