3HL4
Crystal structure of a mammalian CTP:phosphocholine cytidylyltransferase with CDP-choline
3HL4 の概要
エントリーDOI | 10.2210/pdb3hl4/pdb |
分子名称 | Choline-phosphate cytidylyltransferase A, [2-CYTIDYLATE-O'-PHOSPHONYLOXYL]-ETHYL-TRIMETHYL-AMMONIUM, GLYCEROL, ... (5 entities in total) |
機能のキーワード | cytidylyltransferase, rossmann fold, phospholipid synthesis, phosphatidylcholine, phosphocholine, ctp, cdp-choline, amphitropic protein, lipid metabolism, nucleotidyltransferase, phosphoprotein, transferase |
由来する生物種 | Rattus norvegicus (rat) |
細胞内の位置 | Cytoplasm, cytosol: P19836 |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 54975.05 |
構造登録者 | |
主引用文献 | Lee, J.,Johnson, J.E.,Ding, Z.,Paetzel, M.,Cornell, R.B. Crystal Structure of a mammalian CTP: Phosphocholine cytidylyltransferase catalytic domain reveals novel active site residues within a highly conserved nucleotidyl-transferase fold J.Biol.Chem., 284:33535-33548, 2009 Cited by PubMed: 19783652DOI: 10.1074/jbc.M109.053363 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.2 Å) |
構造検証レポート
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