3HK1

Identification and Characterization of a Small Molecule Inhibitor of Fatty Acid Binding Proteins

Summary for 3HK1

• Entry DOI: 10.2210/pdb3hk1/pdb
• Descriptor: Fatty acid-binding protein, adipocyte, 4-{[2-(methoxycarbonyl)-5-(2-thienyl)-3-thienyl]amino}-4-oxo-2-butenoic acid (3 entities in total)
• Functional Keywords: lipid binding protein, fatty acid binding protein, cytoplasm, lipid-binding, nucleus, phosphoprotein, transport, protein binding
• Biological source: Mus musculus (mouse)
• Cellular location: Cytoplasm: P04117
• Total number of polymer chains: 1
• Total formula weight: 14877.06

Authors

Hertzel, A.V.,Hellberg, K.,Reynolds, J.M.,Kruse, A.C.,Juhlmann, B.E.,Smith, A.J.,Sanders, M.A.,Ohlendorf, D.H.,Suttles, J.,Bernlohr, D.A. (deposition date: 2009-05-22, release date: 2009-09-22, Last modification date: 2023-09-06)

• Primary citation: Hertzel, A.V.,Hellberg, K.,Reynolds, J.M.,Kruse, A.C.,Juhlmann, B.E.,Smith, A.J.,Sanders, M.A.,Ohlendorf, D.H.,Suttles, J.,Bernlohr, D.A.; Identification and characterization of a small molecule inhibitor of Fatty Acid binding proteins.; J.Med.Chem., 52:6024-6031, 2009; PubMed: 19754198; DOI: 10.1021/jm900720m

Experimental method

X-RAY DIFFRACTION (1.7 Å)