3HI5
Crystal structure of Fab fragment of AL-57
Summary for 3HI5
Entry DOI | 10.2210/pdb3hi5/pdb |
Related | 3HI6 |
Descriptor | Heavy chain of Fab fragment of AL-57 against alpha L I domain, light chain of Fab fragment of AL-57 against alpha L I domain (3 entities in total) |
Functional Keywords | fab fragment, ligand mimetic, integrin, i domain, cell adhesion, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 46781.93 |
Authors | |
Primary citation | Zhang, H.,Liu, J.H.,Yang, W.,Springer, T.,Shimaoka, M.,Wang, J.H. Structural basis of activation-dependent binding of ligand-mimetic antibody AL-57 to integrin LFA-1. Proc.Natl.Acad.Sci.USA, 106:18345-18350, 2009 Cited by PubMed: 19805116DOI: 10.1073/pnas.0909301106 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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