3HGX

Crystal Structure of Pseudomonas aeruginosa Isochorismate-Pyruvate Lyase K42A mutant in complex with salicylate and pyruvate

3HGX の概要

• エントリーDOI: 10.2210/pdb3hgx/pdb
• 関連するPDBエントリー: 2H9C 2H9D 3HGW
• 分子名称: Salicylate biosynthesis protein pchB, 2-HYDROXYBENZOIC ACID, PYRUVIC ACID, ... (4 entities in total)
• 機能のキーワード: siderophore biosynthesis, pyochelin, isochorismate-pyruvate lyase, chorismate mutase, pchb, lyase
• 由来する生物種: Pseudomonas aeruginosa
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 23230.29

構造登録者

Luo, Q.,Lamb, A.L. (登録日: 2009-05-14, 公開日: 2009-06-30, 最終更新日: 2023-11-15)

• 主引用文献: Luo, Q.,Olucha, J.,Lamb, A.L.; Structure-function analyses of isochorismate-pyruvate lyase from Pseudomonas aeruginosa suggest differing catalytic mechanisms for the two pericyclic reactions of this bifunctional enzyme.; Biochemistry, 48:5239-5245, 2009; PubMed: 19432488; DOI: 10.1021/bi900456e

実験手法

X-RAY DIFFRACTION (2.5 Å)