3HEQ

Human prion protein variant D178N with M129

Summary for 3HEQ

Entry DOI	10.2210/pdb3heq/pdb
Related	3HAF 3HAK 3HER 3HES
Descriptor	Major prion protein, CADMIUM ION (3 entities in total)
Functional Keywords	prion protein, cell membrane, disease mutation, disulfide bond, glycoprotein, golgi apparatus, gpi-anchor, lipoprotein, membrane, polymorphism, prion, membrane protein
Biological source	Homo sapiens (human)
Cellular location	Cell membrane; Lipid-anchor, GPI-anchor . Isoform 2: Cytoplasm : P04156
Total number of polymer chains	2
Total formula weight	32560.85
Authors	Lee, S.,Antony, L.,Hartmann, R.,Knaus, K.J.,Surewicz, K.,Surewicz, W.K.,Yee, V.C. (deposition date: 2009-05-10, release date: 2010-01-12, Last modification date: 2021-10-13)
Primary citation	Lee, S.,Antony, L.,Hartmann, R.,Knaus, K.J.,Surewicz, K.,Surewicz, W.K.,Yee, V.C. Conformational diversity in prion protein variants influences intermolecular beta-sheet formation. Embo J., 29:251-262, 2010 Cited by PubMed: 19927125 DOI: 10.1038/emboj.2009.333 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation