3HCN
Hg and protoporphyrin bound Human Ferrochelatase
Summary for 3HCN
Entry DOI | 10.2210/pdb3hcn/pdb |
Related | 3HCO 3HCP 3HCR |
Descriptor | Ferrochelatase, mitochondrial, FE2/S2 (INORGANIC) CLUSTER, CHOLIC ACID, ... (9 entities in total) |
Functional Keywords | ferrochelatase, metal selectivity, disease mutation, heme biosynthesis, iron, iron-sulfur, lyase, membrane, metal-binding, mitochondrion, mitochondrion inner membrane, porphyrin biosynthesis, transit peptide |
Biological source | Homo sapiens (human) |
Cellular location | Mitochondrion inner membrane; Peripheral membrane protein; Matrix side: P22830 |
Total number of polymer chains | 2 |
Total formula weight | 86128.16 |
Authors | Medlock, A.E.,Dailey, H.A.,Lanzilotta, W.N. (deposition date: 2009-05-06, release date: 2009-11-10, Last modification date: 2024-02-21) |
Primary citation | Medlock, A.E.,Carter, M.,Dailey, T.A.,Dailey, H.A.,Lanzilotta, W.N. Product release rather than chelation determines metal specificity for ferrochelatase. J.Mol.Biol., 393:308-319, 2009 Cited by PubMed: 19703464DOI: 10.1016/j.jmb.2009.08.042 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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