3HBW

Crystal Structure of Human Fibroblast Growth Factor Homologous Factor 2A (FHF2A), also referred to as Fibroblast Growth Factor 13A (FGF13A)

3HBW の概要

• エントリーDOI: 10.2210/pdb3hbw/pdb
• 関連するPDBエントリー: 1Q1U
• 分子名称: Fibroblast growth factor 13 (2 entities in total)
• 機能のキーワード: beta-trefoil fold, alternative splicing, growth factor, polymorphism, hormone
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 43685.74

構造登録者

Mohammadi, M. (登録日: 2009-05-05, 公開日: 2009-05-26, 最終更新日: 2023-09-06)

• 主引用文献: Goetz, R.,Dover, K.,Laezza, F.,Shtraizent, N.,Huang, X.,Tchetchik, D.,Eliseenkova, A.V.,Xu, C.F.,Neubert, T.A.,Ornitz, D.M.,Goldfarb, M.,Mohammadi, M.; Crystal structure of a fibroblast growth factor homologous factor (FHF) defines a conserved surface on FHFs for binding and modulation of voltage-gated sodium channels.; J.Biol.Chem., 284:17883-17896, 2009; PubMed: 19406745; DOI: 10.1074/jbc.M109.001842

実験手法

X-RAY DIFFRACTION (1.9 Å)