3HAD

BIOCHEMICAL CHARACTERIZATION AND STRUCTURE DETERMINATION OF HUMAN HEART SHORT CHAIN L-3-HYDROXYACYL COA DEHYDROGENASE PROVIDE INSIGHT INTO CATALYTIC MECHANISM

3HAD の概要

• エントリーDOI: 10.2210/pdb3had/pdb
• 分子名称: PROTEIN (L-3-HYDROXYACYL COA DEHYDROGENASE), NICOTINAMIDE-ADENINE-DINUCLEOTIDE (3 entities in total)
• 機能のキーワード: oxidoreductase, beta oxidation, schad, catalytic activity: l-3-hydroxyacyl-coa + nad(+) = 3-oxoacyl-coa + nadh
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Mitochondrion matrix: Q16836
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 68742.05

構造登録者

Barycki, J.J.,Bratt, J.M.,Banaszak, L.J. (登録日: 1998-12-03, 公開日: 2000-01-12, 最終更新日: 2022-12-21)

• 主引用文献: Barycki, J.J.,O'Brien, L.K.,Bratt, J.M.,Zhang, R.,Sanishvili, R.,Strauss, A.W.,Banaszak, L.J.; Biochemical characterization and crystal structure determination of human heart short chain L-3-hydroxyacyl-CoA dehydrogenase provide insights into catalytic mechanism.; Biochemistry, 38:5786-5798, 1999; PubMed: 10231530; DOI: 10.1021/bi9829027

実験手法

X-RAY DIFFRACTION (2 Å)