3H99

Structure of a mutant methionyl-tRNA synthetase with modified specificity complexed with methionine

3H99 の概要

• エントリーDOI: 10.2210/pdb3h99/pdb
• 関連するPDBエントリー: 1QQT 3H97 3H9B 3H9C
• 分子名称: Methionyl-tRNA synthetase, METHIONINE, ZINC ION, ... (5 entities in total)
• 機能のキーワード: rossmann fold, aminoacyl-trna synthetase, atp-binding, ligase, metal-binding, nucleotide-binding, protein biosynthesis, rna-binding, trna-binding
• 由来する生物種: Escherichia coli
• 細胞内の位置: Cytoplasm: P00959
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 64506.07

構造登録者

Schmitt, E.,Tanrikulu, I.C.,Yoo, T.H.,Panvert, M.,Tirrell, D.A.,Mechulam, Y. (登録日: 2009-04-30, 公開日: 2009-12-08, 最終更新日: 2023-09-06)

• 主引用文献: Schmitt, E.,Tanrikulu, I.C.,Yoo, T.H.,Panvert, M.,Tirrell, D.A.,Mechulam, Y.; Switching from an induced-fit to a lock-and-key mechanism in an aminoacyl-tRNA synthetase with modified specificity.; J.Mol.Biol., 394:843-851, 2009; PubMed: 19837083; DOI: 10.1016/j.jmb.2009.10.016

実験手法

X-RAY DIFFRACTION (1.4 Å)