3H8R

Structure determination of DNA methylation lesions N1-meA and N3-meC in duplex DNA using a cross-linked host-guest system

Summary for 3H8R

• Entry DOI: 10.2210/pdb3h8r/pdb
• Related: 3H8O 3H8X
• Descriptor: Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2, 5'-D(*CP*TP*GP*TP*AP*TP*(2YR)P*AP*TP*(6MA)P*GP*CP*G)-3', 5'-D(*TP*CP*GP*CP*TP*AP*TP*AP*AP*TP*AP*CP*A)-3', ... (6 entities in total)
• Functional Keywords: protein-dna complex, dioxygenase, dna damage, dna repair, iron, metal-binding, nucleus, oxidoreductase-dna complex, oxidoreductase/dna
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus : Q6NS38
• Total number of polymer chains: 3
• Total formula weight: 31895.67

Authors

Lu, L.,Yi, C.,Jian, X.,Zheng, G.,He, C. (deposition date: 2009-04-29, release date: 2010-03-31, Last modification date: 2021-10-13)

• Primary citation: Lu, L.,Yi, C.,Jian, X.,Zheng, G.,He, C.; Structure determination of DNA methylation lesions N1-meA and N3-meC in duplex DNA using a cross-linked protein-DNA system.; Nucleic Acids Res., 38:4415-4425, 2010; PubMed: 20223766; DOI: 10.1093/nar/gkq129

Experimental method

X-RAY DIFFRACTION (1.77 Å)