3H44

Crystal Structure of Insulin Degrading Enzyme in Complex with macrophage inflammatory protein 1 alpha

Summary for 3H44

• Entry DOI: 10.2210/pdb3h44/pdb
• Descriptor: Insulin-degrading enzyme, C-C motif chemokine 3, 1,4-DIETHYLENE DIOXIDE, ... (5 entities in total)
• Functional Keywords: ide, mip1alpha, cytoplasm, hydrolase, metal-binding, metalloprotease, polymorphism, protease, zinc, chemotaxis, cytokine, disulfide bond, inflammatory response, secreted, hydrolase-cytokine complex, hydrolase/cytokine
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: P14735; Secreted: P10147
• Total number of polymer chains: 4
• Total formula weight: 245367.93

Authors

Ren, M.,Guo, Q.,Tang, W.J. (deposition date: 2009-04-17, release date: 2010-04-14, Last modification date: 2023-09-06)

• Primary citation: Ren, M.,Guo, Q.,Tang, W.J.; Macrophage Inflammatory Protein-1 Is A Novel High Affinity Substrate For Human Insulin Degrading Enzyme; To be Published,

Experimental method

X-RAY DIFFRACTION (3 Å)