3H44

Crystal Structure of Insulin Degrading Enzyme in Complex with macrophage inflammatory protein 1 alpha

3H44 の概要

• エントリーDOI: 10.2210/pdb3h44/pdb
• 分子名称: Insulin-degrading enzyme, C-C motif chemokine 3, 1,4-DIETHYLENE DIOXIDE, ... (5 entities in total)
• 機能のキーワード: ide, mip1alpha, cytoplasm, hydrolase, metal-binding, metalloprotease, polymorphism, protease, zinc, chemotaxis, cytokine, disulfide bond, inflammatory response, secreted, hydrolase-cytokine complex, hydrolase/cytokine
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm: P14735; Secreted: P10147
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 245367.93

構造登録者

Ren, M.,Guo, Q.,Tang, W.J. (登録日: 2009-04-17, 公開日: 2010-04-14, 最終更新日: 2023-09-06)

• 主引用文献: Ren, M.,Guo, Q.,Tang, W.J.; Macrophage Inflammatory Protein-1 Is A Novel High Affinity Substrate For Human Insulin Degrading Enzyme; To be Published,

実験手法

X-RAY DIFFRACTION (3 Å)