3H2V

Human raver1 RRM1 domain in complex with human vinculin tail domain Vt

Summary for 3H2V

• Entry DOI: 10.2210/pdb3h2v/pdb
• Related: 1RKE 1tr2 3H2U
• Descriptor: Vinculin, Raver-1 (3 entities in total)
• Functional Keywords: focal adhesion, actin cytoskeleton, rnp motif, rna binding, alternative splicing, cytoplasm, nucleus, phosphoprotein, rna-binding, cell adhesion
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus (By similarity): Q8IY67
• Total number of polymer chains: 8
• Total formula weight: 119004.69

Authors

Lee, J.H.,Rangarajan, E.S.,Yogesha, S.D.,Izard, T. (deposition date: 2009-04-14, release date: 2009-07-28, Last modification date: 2023-09-06)

• Primary citation: Lee, J.H.,Rangarajan, E.S.,Yogesha, S.D.,Izard, T.; Raver1 interactions with vinculin and RNA suggest a feed-forward pathway in directing mRNA to focal adhesions; Structure, 17:833-842, 2009; PubMed: 19523901; DOI: 10.1016/j.str.2009.04.010

Experimental method

X-RAY DIFFRACTION (2.9 Å)