3H1U

Structure of ubiquitin in complex with Cd ions

3H1U の概要

• エントリーDOI: 10.2210/pdb3h1u/pdb
• 関連するPDBエントリー: 1AAR 1F9J 1TBE 1UBQ 2JF5 2O6V
• 分子名称: Ubiquitin, CADMIUM ION (3 entities in total)
• 機能のキーワード: cadmium bound ubiquitin, isopeptide bond, nucleus, phosphoprotein, signaling protein
• 由来する生物種: Bos taurus (bovine)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 17715.72

構造登録者

Qureshi, I.A.,Ferron, F.,Cheung, P.,Lescar, J. (登録日: 2009-04-14, 公開日: 2009-05-05, 最終更新日: 2023-11-01)

主引用文献

Qureshi, I.A.,Ferron, F.,Seh, C.C.,Cheung, P.,Lescar, J.
Crystallographic structure of ubiquitin in complex with cadmium ions
BMC RES NOTES, 2:251-251, 2009

PubMed Abstract: Ubiquitination plays a critical role in regulating many cellular processes, from DNA repair and gene transcription to cell cycle and apoptosis. It is catalyzed by a specific enzymatic cascade ultimately leading to the conjugation of ubiquitin to lysine residues of the target protein that can be the ubiquitin molecule itself and to the formation of poly-ubiquitin chains.

PubMed: 20003470
DOI: 10.1186/1756-0500-2-251

実験手法

X-RAY DIFFRACTION (3 Å)