3H03

Crystal structure of the binding domain of the AMPA subunit GluR2 bound to UBP277

3H03 の概要

• エントリーDOI: 10.2210/pdb3h03/pdb
• 関連するPDBエントリー: 3H06
• 分子名称: Glutamate receptor 2, 3-[3-(2-carboxyethyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl]-L-alanine, ZINC ION, ... (4 entities in total)
• 機能のキーワード: glutamate receptor, glur2, ampa receptor, neurotransmitter receptor, s1s2, membrane protein
• 由来する生物種: Rattus norvegicus (Rat); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 116949.46

構造登録者

Ahmed, A.H.,Oswald, R.E. (登録日: 2009-04-08, 公開日: 2009-05-05, 最終更新日: 2023-09-06)

• 主引用文献: Ahmed, A.H.,Thompson, M.D.,Fenwick, M.K.,Romero, B.,Loh, A.P.,Jane, D.E.,Sondermann, H.,Oswald, R.E.; Mechanisms of antagonism of the GluR2 AMPA receptor: structure and dynamics of the complex of two willardiine antagonists with the glutamate binding domain.; Biochemistry, 48:3894-3903, 2009; PubMed: 19284741; DOI: 10.1021/bi900107m

実験手法

X-RAY DIFFRACTION (1.9 Å)