3GXZ

Crystal structure of cyanovirin-n complexed to oligomannose-9 (man-9)

「1M5M」から置き換えられました

3GXZ の概要

• エントリーDOI: 10.2210/pdb3gxz/pdb
• 関連するPDBエントリー: 1M5J 1M5M 3GXY
• 分子名称: Cyanovirin-N, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose, ... (6 entities in total)
• 機能のキーワード: cyanovirin-n, hiv-inactivating, domain-swapping, gp120, man-9, oligosaccharide, antiviral protein, disulfide bond, protein synthesis inhibitor
• 由来する生物種: Nostoc ellipsosporum
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 24663.88

構造登録者

Botos, I.,O'Keefe, B.R.,Shenoy, S.R.,Seeberger, P.H.,Boyd, M.R.,Wlodawer, A. (登録日: 2009-04-03, 公開日: 2009-04-14, 最終更新日: 2023-09-06)

• 主引用文献: Botos, I.,O'Keefe, B.R.,Shenoy, S.R.,Cartner, L.K.,Ratner, D.M.,Seeberger, P.H.,Boyd, M.R.,Wlodawer, A.; Structures of the complexes of a potent anti-HIV protein cyanovirin-N and high mannose oligosaccharides; J.Biol.Chem., 277:34336-34342, 2002; PubMed: 12110688; DOI: 10.1074/jbc.M205909200

実験手法

X-RAY DIFFRACTION (2.5 Å)