3GVB
AmpC beta-lactamase in complex with Fragment-based Inhibitor
Summary for 3GVB
Entry DOI | 10.2210/pdb3gvb/pdb |
Related | 3GQZ 3GR2 3GRJ 3GSG 3GTC 3GV9 |
Descriptor | Beta-lactamase, PHOSPHATE ION, (3S)-1-(2-hydroxyphenyl)-5-oxopyrrolidine-3-carboxylic acid, ... (5 entities in total) |
Functional Keywords | hydrolase, antibiotic resistance, periplasm, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Escherichia coli |
Cellular location | Periplasm: P00811 |
Total number of polymer chains | 2 |
Total formula weight | 80089.47 |
Authors | Teotico, D.T.,Shoichet, B.K. (deposition date: 2009-03-30, release date: 2009-04-14, Last modification date: 2023-09-06) |
Primary citation | Teotico, D.G.,Babaoglu, K.,Rocklin, G.J.,Ferreira, R.S.,Giannetti, A.M.,Shoichet, B.K. Docking for fragment inhibitors of AmpC beta-lactamase Proc.Natl.Acad.Sci.USA, 106:7455-7460, 2009 Cited by PubMed: 19416920DOI: 10.1073/pnas.0813029106 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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