3GUT

Crystal structure of a higher-order complex of p50:RelA bound to the HIV-1 LTR

3GUT の概要

• エントリーDOI: 10.2210/pdb3gut/pdb
• 関連するPDBエントリー: 1P7H 1VKX 2O93
• 分子名称: Transcription factor p65, Nuclear factor NF-kappa-B p105 subunit, HIV-LTR Core Forward Strand, ... (4 entities in total)
• 機能のキーワード: ig fold, protein-dna complex, pseudocontinuous helix, rel family, multiprotein assembly, acetylation, activator, alternative splicing, cytoplasm, dna-binding, nucleus, phosphoprotein, transcription, transcription regulation, ubl conjugation, ank repeat, apoptosis, polymorphism, s-nitrosylation, transcription-dna complex, transcription/dna
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Nucleus: Q04206 P19838
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 295590.26

構造登録者

Stroud, J.C.,Oltman, A.J.,Han, A.,Bates, D.L.,Chen, L. (登録日: 2009-03-30, 公開日: 2009-09-08, 最終更新日: 2023-09-06)

• 主引用文献: Stroud, J.C.,Oltman, A.,Han, A.,Bates, D.L.,Chen, L.; Structural basis of HIV-1 activation by NF-kappaB--a higher-order complex of p50:RelA bound to the HIV-1 LTR.; J.Mol.Biol., 393:98-112, 2009; PubMed: 19683540; DOI: 10.1016/j.jmb.2009.08.023

実験手法

X-RAY DIFFRACTION (3.59 Å)