3GUK
T4 lysozyme M102E/L99A mutant with buried charge in apolar cavity--Toluene binding
Summary for 3GUK
Entry DOI | 10.2210/pdb3guk/pdb |
Related | 3GUI 3GUJ 3GUL 3GUM 3GUN 3GUO 3GUP |
Descriptor | Lysozyme, TOLUENE, CALCIUM ION, ... (6 entities in total) |
Functional Keywords | t4 lysozyme, apolar cavity, buried charge, ligand binding, antimicrobial, bacteriolytic enzyme, glycosidase, hydrolase |
Biological source | Enterobacteria phage T4 |
Cellular location | Host cytoplasm : P00720 |
Total number of polymer chains | 2 |
Total formula weight | 37867.94 |
Authors | Liu, L.,Matthews, B.W. (deposition date: 2009-03-30, release date: 2009-08-25, Last modification date: 2023-09-06) |
Primary citation | Liu, L.,Baase, W.A.,Michael, M.M.,Matthews, B.W. Use of stabilizing mutations to engineer a charged group within a ligand-binding hydrophobic cavity in T4 lysozyme. Biochemistry, 48:8842-8851, 2009 Cited by PubMed: 19663503DOI: 10.1021/bi900685j PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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