3GSQ
Crystal structure of the binary complex between HLA-A2 and HCMV NLV-M5S peptide variant
Summary for 3GSQ
Entry DOI | 10.2210/pdb3gsq/pdb |
Related | 3GSN 3GSO 3GSR 3GSU 3GSV 3GSW 3GSX |
Descriptor | HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, HCMV pp65 fragment 495-503, variant M5S (NLVPSVATV), ... (4 entities in total) |
Functional Keywords | hla, human cytomegalovirus, pp65, t cell receptor (tcr), immune response, public response, immunodominance, restrained response, host-virus interaction, membrane, mhc i, polymorphism, immunoglobulin domain, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P01892 Secreted: P61769 |
Total number of polymer chains | 3 |
Total formula weight | 44531.54 |
Authors | Reiser, J.-B.,Saulquin, X.,Gras, S.,Debeaupuis, E.,Echasserieau, K.,Kissenpfennig, A.,Legoux, F.,Chouquet, A.,Le Gorrec, M.,Machillot, P.,Neveu, B.,Thielens, N.,Malissen, B.,Bonneville, M.,Housset, D. (deposition date: 2009-03-27, release date: 2009-08-04, Last modification date: 2021-10-20) |
Primary citation | Gras, S.,Saulquin, X.,Reiser, J.B.,Debeaupuis, E.,Echasserieau, K.,Kissenpfennig, A.,Legoux, F.,Chouquet, A.,Le Gorrec, M.,Machillot, P.,Neveu, B.,Thielens, N.,Malissen, B.,Bonneville, M.,Housset, D. Structural bases for the affinity-driven selection of a public TCR against a dominant human cytomegalovirus epitope. J.Immunol., 183:430-437, 2009 Cited by PubMed: 19542454DOI: 10.4049/jimmunol.0900556 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.12 Å) |
Structure validation
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