3GSQ
Crystal structure of the binary complex between HLA-A2 and HCMV NLV-M5S peptide variant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HLA class I histocompatibility antigen, A-2 alpha chain | polymer | 274 | 31753.1 | 1 | UniProt (P01892) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P04439) | Homo sapiens (human) | MHC class I antigen A*2 |
| 2 | B (B) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | Beta-2-microglobulin form pI 5.3 |
| 3 | C (P) | HCMV pp65 fragment 495-503, variant M5S (NLVPSVATV) | polymer | 9 | 899.0 | 1 | |||
| 4 | D, E, F (A, B, P) | water | water | 18.0 | 168 | Chemie (HOH) |
Sequence modifications
A: 1 - 274 (UniProt: P01892)
B: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Val 245 | Ala 269 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 44531.5 | |
| All* | Total formula weight | 44531.5 |
