Summary for 3GQE
| Related | 3GPG 3GPO 3GPQ |
|---|---|
| Descriptor | Non-structural protein 3, BICINE (3 entities in total) |
| Functional Keywords | macro domain, x domain, venezuelan equine encephalitis virus, alphavirus, virus, vizier. viral enzymes involved in replication, atp-binding, cell membrane, cell projection, endosome, helicase, hydrolase, lipoprotein, lysosome, membrane, methyltransferase, mrna capping, mrna processing, multifunctional enzyme, nucleotide-binding, nucleotidyltransferase, nucleus, palmitate, phosphoprotein, protease, rna replication, rna-binding, rna-directed rna polymerase, thiol protease, transferase, viral protein |
| Biological source | Venezuelan equine encephalitis virus |
| Cellular location | Non-structural polyprotein: Host endosome membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). P123: Host endosome membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). P123': Host endosome membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). mRNA-capping enzyme nsP1: Host endosome membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). Protease nsP2: Host endosome membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). Non-structural protein 3: Host endosome membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). Non-structural protein 3': Host endosome membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). RNA-directed RNA polymerase nsP4: Host endosome membrane; Peripheral membrane protein; Cytoplasmic side (By similarity) P36328 |
| Total number of polymer chains | 2 |
| Total molecular weight | 36892.91 |
| Authors | Jamal, S.,Malet, H.,Coutard, B.,Canard, B. (deposition date: 2009-03-24, release date: 2009-07-21, Last modification date: 2011-07-13) |
| Primary citation | Malet, H.,Coutard, B.,Jamal, S.,Dutartre, H.,Papageorgiou, N.,Neuvonen, M.,Ahola, T.,Forrester, N.,Gould, E.A.,Lafitte, D.,Ferron, F.,Lescar, J.,Gorbalenya, A.E.,de Lamballerie, X.,Canard, B. The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket J.Virol., 83:6534-6545, 2009 PubMed: 19386706 (PDB entries with the same primary citation) DOI: 10.1128/JVI.00189-09  Import into Mendeley |
| Experimental method | X-RAY DIFFRACTION (2.3 Å) |
