3GPU

MutM encountering an intrahelical 8-oxoguanine (oxoG) lesion in EC4-loop deletion complex

3GPU の概要

• エントリーDOI: 10.2210/pdb3gpu/pdb
• 関連するPDBエントリー: 3GPP 3GPX 3GPY 3GQ3 3GQ4 3GQ5
• 分子名称: DNA glycosylase, DNA (5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*TP*CP*GP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*CP*CP*(8OG)P*AP*GP*TP*CP*TP*AP*CP*C)-3'), ... (5 entities in total)
• 機能のキーワード: dna glycosylase, dna repair, damage search, base extrusion, disulfide crosslinking, dna damage, dna-binding, glycosidase, hydrolase, lyase, metal-binding, multifunctional enzyme, zinc-finger, lyase-dna complex, lyase/dna
• 由来する生物種: Geobacillus stearothermophilus (Geobacillus stearothermophilus)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 38692.24

構造登録者

Banerjee, A.,Qi, Y.,Verdine, G.L. (登録日: 2009-03-23, 公開日: 2009-11-10, 最終更新日: 2023-09-06)

• 主引用文献: Qi, Y.,Spong, M.C.,Nam, K.,Banerjee, A.,Jiralerspong, S.,Karplus, M.,Verdine, G.L.; Encounter and extrusion of an intrahelical lesion by a DNA repair enzyme.; Nature, 462:762-766, 2009; PubMed: 20010681; DOI: 10.1038/nature08561

実験手法

X-RAY DIFFRACTION (1.62 Å)