3GPG
Crystal structure of macro domain of Chikungunya virus
3GPG の概要
エントリーDOI | 10.2210/pdb3gpg/pdb |
関連するPDBエントリー | 3GPO 3GPQ |
分子名称 | Non-structural protein 3 (2 entities in total) |
機能のキーワード | macro domain, x domain, chikungunya, alphavirus, virus, vizier. viral enzymes involved in replication, atp-binding, cell membrane, endosome, helicase, hydrolase, lipoprotein, lysosome, membrane, methyltransferase, mrna capping, mrna processing, multifunctional enzyme, nucleotide-binding, nucleotidyltransferase, nucleus, palmitate, phosphoprotein, protease, rna replication, rna-binding, rna-directed rna polymerase, thiol protease, transferase, viral protein |
由来する生物種 | Chikungunya virus |
細胞内の位置 | Non-structural polyprotein: Host endosome membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). P123: Host endosome membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). mRNA-capping enzyme nsP1: Host endosome membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). Protease nsP2: Host endosome membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). Non-structural protein 3: Host endosome membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). RNA-directed RNA polymerase nsP4: Host endosome membrane; Peripheral membrane protein; Cytoplasmic side (By similarity): Q8JUX6 |
タンパク質・核酸の鎖数 | 4 |
化学式量合計 | 74540.49 |
構造登録者 | |
主引用文献 | Malet, H.,Coutard, B.,Jamal, S.,Dutartre, H.,Papageorgiou, N.,Neuvonen, M.,Ahola, T.,Forrester, N.,Gould, E.A.,Lafitte, D.,Ferron, F.,Lescar, J.,Gorbalenya, A.E.,de Lamballerie, X.,Canard, B. The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket J.Virol., 83:6534-6545, 2009 Cited by PubMed: 19386706DOI: 10.1128/JVI.00189-09 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.65 Å) |
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