3GOV
Crystal structure of the catalytic region of human MASP-1
Summary for 3GOV
Entry DOI | 10.2210/pdb3gov/pdb |
Descriptor | MASP-1, GLYCEROL, ... (4 entities in total) |
Functional Keywords | complement, serine protease, beta barrel, hydrolase, hydroxylation, immune response, innate immunity, sushi, coagulation, complement pathway, disulfide bond, egf-like domain, glycoprotein, protease |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P48740 P48740 |
Total number of polymer chains | 2 |
Total formula weight | 45721.33 |
Authors | Harmat, V.,Dobo, J.,Beinrohr, L.,Sebestyen, E.,Zavodszky, P.,Gal, P. (deposition date: 2009-03-20, release date: 2009-06-09, Last modification date: 2023-09-06) |
Primary citation | Dobo, J.,Harmat, V.,Beinrohr, L.,Sebestyen, E.,Zavodszky, P.,Gal, P. MASP-1, a promiscuous complement protease: structure of its catalytic region reveals the basis of its broad specificity. J.Immunol., 183:1207-1214, 2009 Cited by PubMed: 19564340DOI: 10.4049/jimmunol.0901141 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.55 Å) |
Structure validation
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