3GOV

Crystal structure of the catalytic region of human MASP-1

3GOV の概要

• エントリーDOI: 10.2210/pdb3gov/pdb
• 分子名称: MASP-1, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: complement, serine protease, beta barrel, hydrolase, hydroxylation, immune response, innate immunity, sushi, coagulation, complement pathway, disulfide bond, egf-like domain, glycoprotein, protease
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted: P48740 P48740
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 45721.33

構造登録者

Harmat, V.,Dobo, J.,Beinrohr, L.,Sebestyen, E.,Zavodszky, P.,Gal, P. (登録日: 2009-03-20, 公開日: 2009-06-09, 最終更新日: 2023-09-06)

• 主引用文献: Dobo, J.,Harmat, V.,Beinrohr, L.,Sebestyen, E.,Zavodszky, P.,Gal, P.; MASP-1, a promiscuous complement protease: structure of its catalytic region reveals the basis of its broad specificity.; J.Immunol., 183:1207-1214, 2009; PubMed: 19564340; DOI: 10.4049/jimmunol.0901141

実験手法

X-RAY DIFFRACTION (2.55 Å)