3GO8

MutM encountering an intrahelical 8-oxoguanine (oxoG) lesion in EC3-loop deletion complex

3GO8 の概要

• エントリーDOI: 10.2210/pdb3go8/pdb
• 関連するPDBエントリー: 3GPP 3GPU 3GPX 3GQ3 3GQ4 3GQ5 3GQY
• 分子名称: Formamidopyrimidine-DNA glycosylase, 5'-D(P*GP*GP*TP*AP*GP*AP*TP*CP*CP*GP*GP*AP*CP*G)-3', 5'-D(*GP*CP*GP*TP*CP*CP*(8OG)P*GP*AP*TP*CP*TP*AP*C)-3', ... (5 entities in total)
• 機能のキーワード: dna glycosylase, dna repair, damage search, base extrusion, disulfide crosslinking, dna damage, dna-binding, glycosidase, hydrolase, lyase, metal-binding, multifunctional enzyme, zinc-finger, lyase-dna complex, lyase/dna
• 由来する生物種: Geobacillus stearothermophilus (Bacillus stearothermophilus); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 38735.26

構造登録者

Spong, M.C.,Qi, Y.,Verdine, G.L. (登録日: 2009-03-18, 公開日: 2009-12-15, 最終更新日: 2023-09-06)

• 主引用文献: Qi, Y.,Spong, M.C.,Nam, K.,Banerjee, A.,Jiralerspong, S.,Karplus, M.,Verdine, G.L.; Encounter and extrusion of an intrahelical lesion by a DNA repair enzyme; Nature, 462:762-766, 2009; PubMed: 20010681; DOI: 10.1038/nature08561

実験手法

X-RAY DIFFRACTION (1.89 Å)