3GO8
MutM encountering an intrahelical 8-oxoguanine (oxoG) lesion in EC3-loop deletion complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Formamidopyrimidine-DNA glycosylase | polymer | 257 | 28855.5 | 1 | UniProt (P84131) Pfam (PF01149) Pfam (PF06831) Pfam (PF06827) | Geobacillus stearothermophilus (Bacillus stearothermophilus) | Fapy-DNA glycosylase,DNA-(apurinic or apyrimidinic site) lyase MutM,AP lyase MutM |
| 2 | B (B) | 5'-D(P*GP*GP*TP*AP*GP*AP*TP*CP*CP*GP*GP*AP*CP*G)-3' | polymer | 16 | 4948.2 | 1 | synthetic construct | ||
| 3 | C (C) | 5'-D(*GP*CP*GP*TP*CP*CP*(8OG)P*GP*AP*TP*CP*TP*AP*C)-3' | polymer | 16 | 4866.1 | 1 | synthetic construct | ||
| 4 | D (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | E, F, G (A, B, C) | water | water | 18.0 | 244 | Chemie (HOH) |
Sequence modifications
A: 2 - 274 (UniProt: P84131)
| PDB | External Database | Details |
|---|---|---|
| Glu 3 | Gln 3 | conflict |
| Cys 166 | Gln 166 | engineered mutation |
| - | Ser 220 | deletion |
| - | Thr 221 | deletion |
| - | Val 222 | deletion |
| - | Arg 223 | deletion |
| - | Thr 224 | deletion |
| - | Tyr 225 | deletion |
| - | Val 226 | deletion |
| - | Thr 228 | deletion |
| - | Gln 229 | deletion |
| - | Gly 230 | deletion |
| - | Glu 231 | deletion |
| - | Ala 232 | deletion |
| - | Gly 233 | deletion |
| - | Thr 234 | deletion |
| - | Phe 235 | deletion |
| - | Gln 236 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 38669.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 65.4 | |
| All* | Total formula weight | 38735.3 |
