3GNI
Structure of STRAD and MO25
Summary for 3GNI
Entry DOI | 10.2210/pdb3gni/pdb |
Related | 1UPK 1UPL |
Descriptor | Protein Mo25, STRAD alpha, CITRIC ACID, ... (5 entities in total) |
Functional Keywords | kinase fold, pseudokinase, alpha helical repeat protein, adaptor protein, atp-binding, cell cycle, kinase, nucleotide-binding, nucleus, phosphoprotein, transferase, metal binding protein-transferase complex, signaling protein-signaling protein complex, signaling protein/signaling protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm (Potential): Q9Y376 Nucleus: Q7RTN6 |
Total number of polymer chains | 2 |
Total formula weight | 84384.86 |
Authors | Zeqiraj, E.,Goldie, S.,Alessi, D.R.,van Aalten, D.M.F. (deposition date: 2009-03-17, release date: 2009-06-16, Last modification date: 2023-09-06) |
Primary citation | Zeqiraj, E.,Filippi, B.M.,Goldie, S.,Navratilova, I.,Boudeau, J.,Deak, M.,Alessi, D.R.,van Aalten, D.M. ATP and MO25alpha regulate the conformational state of the STRADalpha pseudokinase and activation of the LKB1 tumour suppressor Plos Biol., 7:e1000126-e1000126, 2009 Cited by PubMed: 19513107DOI: 10.1371/journal.pbio.1000126 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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