3GLR

Crystal Structure of human SIRT3 with acetyl-lysine AceCS2 peptide

Summary for 3GLR

• Entry DOI: 10.2210/pdb3glr/pdb
• Related: 3GLS 3GLT 3GLU
• Descriptor: NAD-dependent deacetylase sirtuin-3, mitochondrial, Acetyl-coenzyme A synthetase 2-like, mitochondrial, ZINC ION, ... (7 entities in total)
• Functional Keywords: nad dependent deacetylase, sirtuin, substrate peptide complex, hydrolase, metal-binding, mitochondrion, nad, transit peptide, ligase, hydrolase-hydrolase regulator complex, hydrolase/hydrolase regulator
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 33541.87

Authors

Jin, L.,Wei, W.,Jiang, Y.,Peng, H.,Cai, J.,Mao, C.,Dai, H.,Bemis, J.E.,Jirousek, M.R.,Milne, J.C.,Westphal, C.H.,Perni, R.B. (deposition date: 2009-03-12, release date: 2009-06-16, Last modification date: 2019-07-24)

• Primary citation: Jin, L.,Wei, W.,Jiang, Y.,Peng, H.,Cai, J.,Mao, C.,Dai, H.,Choy, W.,Bemis, J.E.,Jirousek, M.R.,Milne, J.C.,Westphal, C.H.,Perni, R.B.; Crystal Structures of Human SIRT3 Displaying Substrate-induced Conformational Changes.; J.Biol.Chem., 284:24394-24405, 2009; PubMed: 19535340; DOI: 10.1074/jbc.M109.014928

Experimental method

X-RAY DIFFRACTION (1.8 Å)