3GL6
Crystal structure of JARID1A-PHD3 complexed with H3(1-9)K4me3 peptide
Summary for 3GL6
Entry DOI | 10.2210/pdb3gl6/pdb |
Descriptor | Histone demethylase JARID1A, Histone H3, ZINC ION, ... (4 entities in total) |
Functional Keywords | phd finger, h3(1-9)k4me3 peptide, leukemia, alternative splicing, chromatin regulator, developmental protein, dioxygenase, iron, metal-binding, nucleus, oxidoreductase, phosphoprotein, polymorphism, transcription, transcription regulation, zinc, zinc-finger, chromosomal protein, dna-binding, nucleosome core |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus, nucleolus: P29375 |
Total number of polymer chains | 2 |
Total formula weight | 7104.05 |
Authors | Wang, Z.,Song, J.,Patel, D.J. (deposition date: 2009-03-11, release date: 2009-05-05, Last modification date: 2011-07-13) |
Primary citation | Wang, G.G.,Song, J.,Wang, Z.,Dormann, H.L.,Casadio, F.,Li, H.,Luo, J.L.,Patel, D.J.,Allis, C.D. Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger. Nature, 459:847-851, 2009 Cited by PubMed: 19430464DOI: 10.1038/nature08036 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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