3GL6
Crystal structure of JARID1A-PHD3 complexed with H3(1-9)K4me3 peptide
3GL6 の概要
エントリーDOI | 10.2210/pdb3gl6/pdb |
分子名称 | Histone demethylase JARID1A, Histone H3, ZINC ION, ... (4 entities in total) |
機能のキーワード | phd finger, h3(1-9)k4me3 peptide, leukemia, alternative splicing, chromatin regulator, developmental protein, dioxygenase, iron, metal-binding, nucleus, oxidoreductase, phosphoprotein, polymorphism, transcription, transcription regulation, zinc, zinc-finger, chromosomal protein, dna-binding, nucleosome core |
由来する生物種 | Homo sapiens (human) 詳細 |
細胞内の位置 | Nucleus, nucleolus: P29375 |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 7104.05 |
構造登録者 | |
主引用文献 | Wang, G.G.,Song, J.,Wang, Z.,Dormann, H.L.,Casadio, F.,Li, H.,Luo, J.L.,Patel, D.J.,Allis, C.D. Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger. Nature, 459:847-851, 2009 Cited by PubMed: 19430464DOI: 10.1038/nature08036 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.9 Å) |
構造検証レポート
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