3GIZ
Crystal structure of the Fab fragment of anti-CD20 antibody Ofatumumab
Summary for 3GIZ
Entry DOI | 10.2210/pdb3giz/pdb |
Descriptor | Fab fragment of anti-CD20 antibody Ofatumumab, light chain, Fab fragment of anti-CD20 antibody Ofatumumab, heavy chain, ZINC ION, ... (4 entities in total) |
Functional Keywords | cd20, 2f2, ofatumumab, hu-maxcd20, fab, antibody, fully human antibody, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 47088.48 |
Authors | |
Primary citation | Du, J.,Yang, H.,Guo, Y.,Ding, J. Structure of the Fab fragment of therapeutic antibody Ofatumumab provides insights into the recognition mechanism with CD20 Mol.Immunol., 46:2419-2423, 2009 Cited by PubMed: 19427037DOI: 10.1016/j.molimm.2009.04.009 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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