3GIZ

Crystal structure of the Fab fragment of anti-CD20 antibody Ofatumumab

Summary for 3GIZ

• Entry DOI: 10.2210/pdb3giz/pdb
• Descriptor: Fab fragment of anti-CD20 antibody Ofatumumab, light chain, Fab fragment of anti-CD20 antibody Ofatumumab, heavy chain, ZINC ION, ... (4 entities in total)
• Functional Keywords: cd20, 2f2, ofatumumab, hu-maxcd20, fab, antibody, fully human antibody, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 47088.48

Authors

Du, J.,Yang, H.,Ding, J. (deposition date: 2009-03-07, release date: 2009-05-26, Last modification date: 2023-11-01)

• Primary citation: Du, J.,Yang, H.,Guo, Y.,Ding, J.; Structure of the Fab fragment of therapeutic antibody Ofatumumab provides insights into the recognition mechanism with CD20; Mol.Immunol., 46:2419-2423, 2009; PubMed: 19427037; DOI: 10.1016/j.molimm.2009.04.009

Experimental method

X-RAY DIFFRACTION (2.2 Å)