3GIZ

Crystal structure of the Fab fragment of anti-CD20 antibody Ofatumumab

3GIZ の概要

分子名称Fab fragment of anti-CD20 antibody Ofatumumab, light chain, Fab fragment of anti-CD20 antibody Ofatumumab, heavy chain, ZINC ION, ... (4 entities in total)
機能のキーワードcd20, 2f2, ofatumumab, hu-maxcd20, fab, antibody, fully human antibody, immune system
由来する生物種Homo sapiens (human)
ポリマー鎖数2
分子量合計47088.48
構造登録者
Du, J.,Yang, H.,Ding, J. (登録日: 2009-03-07, 公開日: 2009-05-26, 最終更新日: 2011-07-13)
主引用文献
Du, J.,Yang, H.,Guo, Y.,Ding, J.
Structure of the Fab fragment of therapeutic antibody Ofatumumab provides insights into the recognition mechanism with CD20
Mol.Immunol., 46:2419-2423, 2009
PubMed: 19427037 (主引用文献が同じPDBエントリー)
DOI: 10.1016/j.molimm.2009.04.009
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2.2 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.197607.4%0.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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