3GIZ

Crystal structure of the Fab fragment of anti-CD20 antibody Ofatumumab

3GIZ の概要

• エントリーDOI: 10.2210/pdb3giz/pdb
• 分子名称: Fab fragment of anti-CD20 antibody Ofatumumab, light chain, Fab fragment of anti-CD20 antibody Ofatumumab, heavy chain, ZINC ION, ... (4 entities in total)
• 機能のキーワード: cd20, 2f2, ofatumumab, hu-maxcd20, fab, antibody, fully human antibody, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 47088.48

構造登録者

Du, J.,Yang, H.,Ding, J. (登録日: 2009-03-07, 公開日: 2009-05-26, 最終更新日: 2023-11-01)

• 主引用文献: Du, J.,Yang, H.,Guo, Y.,Ding, J.; Structure of the Fab fragment of therapeutic antibody Ofatumumab provides insights into the recognition mechanism with CD20; Mol.Immunol., 46:2419-2423, 2009; PubMed: 19427037; DOI: 10.1016/j.molimm.2009.04.009

実験手法

X-RAY DIFFRACTION (2.2 Å)