3GI0
Crystal structure of a chemically synthesized 203 amino acid 'covalent dimer' [l-ala51,d-ala51'] hiv-1 protease molecule complexed with jg-365 inhibitor
Summary for 3GI0
Entry DOI | 10.2210/pdb3gi0/pdb |
Related | 3FSM |
Related PRD ID | PRD_000228 |
Descriptor | COVALENT DIMER [L-ALA51,D-ALA51'] HIV-1 PROTEASE, JG-365 inhibitor (3 entities in total) |
Functional Keywords | beta-barrel, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Gag-Pol polyprotein: Host cell membrane; Lipid-anchor. Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion : P03369 |
Total number of polymer chains | 4 |
Total formula weight | 45529.48 |
Authors | Torbeev, V.Y.,Kent, S.B.H. (deposition date: 2009-03-04, release date: 2011-08-10, Last modification date: 2023-11-15) |
Primary citation | Torbeev, V.Y.,Kent, S.B.H. Correlations of protein dynamics with function in HIV-1 protease catalysis To be Published, |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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