3GD8

Crystal Structure of Human Aquaporin 4 at 1.8 and its Mechanism of Conductance

3GD8 の概要

• エントリーDOI: 10.2210/pdb3gd8/pdb
• 分子名称: Aquaporin-4, GLYCEROL, octyl beta-D-glucopyranoside, ... (4 entities in total)
• 機能のキーワード: brain edema, aquaporin, proton exclusion, structural genomics, psi-2, protein structure initiative, center for structures of membrane proteins, csmp, glycoprotein, membrane, phosphoprotein, transmembrane, transport, membrane protein
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 24279.58

構造登録者

Ho, J.D.,Yeh, R.,Sandstrom, A.,Chorny, I.,Harries, W.E.C.,Robbins, R.A.,Miercke, L.J.W.,Stroud, R.M.,Center for Structures of Membrane Proteins (CSMP) (登録日: 2009-02-23, 公開日: 2009-03-31, 最終更新日: 2024-02-21)

• 主引用文献: Ho, J.D.,Yeh, R.,Sandstrom, A.,Chorny, I.,Harries, W.E.,Robbins, R.A.,Miercke, L.J.,Stroud, R.M.; Crystal structure of human aquaporin 4 at 1.8 A and its mechanism of conductance.; Proc.Natl.Acad.Sci.USA, 106:7437-7442, 2009; PubMed: 19383790; DOI: 10.1073/pnas.0902725106

実験手法

X-RAY DIFFRACTION (1.8 Å)