3GCP

Human P38 MAP Kinase in Complex with SB203580

Summary for 3GCP

Entry DOI	10.2210/pdb3gcp/pdb
Related	3GCV
Descriptor	Mitogen-activated protein kinase 14, 4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE, octyl beta-D-glucopyranoside, ... (4 entities in total)
Functional Keywords	dfg-out, type i, sb203580, alternative splicing, atp-binding, cytoplasm, kinase, nucleotide-binding, nucleus, phosphoprotein, polymorphism, serine/threonine-protein kinase, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	42197.15
Authors	Gruetter, C.,Simard, J.R.,Rauh, D. (deposition date: 2009-02-22, release date: 2009-06-09, Last modification date: 2023-09-06)
Primary citation	Simard, J.R.,Getlik, M.,Grutter, C.,Pawar, V.,Wulfert, S.,Rabiller, M.,Rauh, D. Development of a fluorescent-tagged kinase assay system for the detection and characterization of allosteric kinase inhibitors. J.Am.Chem.Soc., 131:13286-13296, 2009 Cited by PubMed: 19572644 DOI: 10.1021/ja902010p PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation