3GAX
Crystal structure of monomeric human cystatin C stabilized against aggregation
Summary for 3GAX
Entry DOI | 10.2210/pdb3gax/pdb |
Related | 1G96 1R4C 1TIJ |
Descriptor | Cystatin-C (2 entities in total) |
Functional Keywords | cysteine protease inhibitor, 3d domain swapping, protein aggregation, amyloid, protein engineering, twinning, hereditary cystatin c amyloid angiopathy, amyloidosis, disease mutation, polymorphism, protease inhibitor, secreted, thiol protease inhibitor, hydrolase inhibitor |
Biological source | Homo sapiens (Human) |
Cellular location | Secreted : P01034 |
Total number of polymer chains | 2 |
Total formula weight | 26802.43 |
Authors | Kolodziejczyk, R.,Michalska, K.,Hernandez-Santoyo, A.,Wahlbom, M.,Grubb, A.,Jaskolski, M. (deposition date: 2009-02-18, release date: 2010-02-23, Last modification date: 2023-09-06) |
Primary citation | Kolodziejczyk, R.,Michalska, K.,Hernandez-Santoyo, A.,Wahlbom, M.,Grubb, A.,Jaskolski, M. Crystal structure of human cystatin C stabilized against amyloid formation. Febs J., 277:1726-1737, 2010 Cited by PubMed: 20175878DOI: 10.1111/j.1742-4658.2010.07596.x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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