3G73

Structure of the FOXM1 DNA binding

Summary for 3G73

• Entry DOI: 10.2210/pdb3g73/pdb
• Descriptor: Forkhead box protein M1, DNA (5'-D(P*AP*AP*AP*TP*TP*GP*TP*TP*TP*AP*TP*AP*AP*AP*CP*AP*GP*CP*CP*CP*G)-3'), DNA (5'-D(P*TP*TP*CP*GP*GP*GP*CP*TP*GP*TP*TP*TP*AP*TP*AP*AP*AP*CP*AP*AP*T)-3'), ... (5 entities in total)
• Functional Keywords: dna-binding domain, forkhead transcription factors, foxm1, winged helix, forkhead, transcription regulation, transcription-dna complex, activator, dna-binding, nucleus, phosphoprotein, transcription, transcription/dna
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus: Q08050
• Total number of polymer chains: 4
• Total formula weight: 46132.72

Authors

Littler, D.R.,Perrakis, A.,Hibbert, R.G.,Medema, R.H. (deposition date: 2009-02-09, release date: 2009-03-03, Last modification date: 2023-11-01)

• Primary citation: Littler, D.R.,Alvarez-Fernandez, M.,Stein, A.,Hibbert, R.G.,Heidebrecht, T.,Aloy, P.,Medema, R.H.,Perrakis, A.; Structure of the FoxM1 DNA-recognition domain bound to a promoter sequence; Nucleic Acids Res., 2010; PubMed: 20360045; DOI: 10.1093/nar/gkq194

Experimental method

X-RAY DIFFRACTION (2.21 Å)