3G73

Structure of the FOXM1 DNA binding

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000086	biological_process	G2/M transition of mitotic cell cycle
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006355	biological_process	regulation of DNA-templated transcription
A	0043565	molecular_function	sequence-specific DNA binding
B	0000086	biological_process	G2/M transition of mitotic cell cycle
B	0003677	molecular_function	DNA binding
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0006355	biological_process	regulation of DNA-templated transcription
B	0043565	molecular_function	sequence-specific DNA binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 996

Chain	Residue
A	HOH24
A	LEU289
A	SER290
A	HIS292
A	PHE295
D	HOH26

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG B 996

Chain	Residue
B	HIS292
B	PHE295
C	HOH46
B	HOH49
B	LEU289
B	SER290

---

Functional Information from PROSITE/UniProt

site_id	PS00657
Number of Residues	14
Details	FORK_HEAD_1 Fork head domain signature 1. RPPYSYmaMiqf.AI

Chain	Residue	Details
A	ARG236-ILE249

---

site_id	PS00658
Number of Residues	7
Details	FORK_HEAD_2 Fork head domain signature 2. WKNSIRH

Chain	Residue	Details
A	TRP281-HIS287

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	92
Details	DNA binding: {"description":"Fork-head","evidences":[{"source":"PROSITE-ProRule","id":"PRU00089","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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