3G6W

Asymetric GTP bound structure of UPRTase from Sulfolobus solfataricus containing PRPP-mg2+ in half of the active sites and R5P and PPi in the other half

3G6W の概要

• エントリーDOI: 10.2210/pdb3g6w/pdb
• 関連するPDBエントリー: 1VST 1XTT 1XTU 1XTV
• 分子名称: Uracil phosphoribosyltransferase, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (7 entities in total)
• 機能のキーワード: allosteric regulation, tetramer, sulfolobus solfataricus, phosphoribosyltransferase, prpp, r5p, gtp, pop, magnesium, glycosyltransferase, transferase
• 由来する生物種: Sulfolobus solfataricus
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 100729.72

構造登録者

Kadziola, A.,Christoffersen, S. (登録日: 2009-02-09, 公開日: 2009-09-01, 最終更新日: 2023-11-01)

• 主引用文献: Christoffersen, S.,Kadziola, A.,Johansson, E.,Rasmussen, M.,Willemoes, M.,Jensen, K.F.; Structural and kinetic studies of the allosteric transition in Sulfolobus solfataricus uracil phosphoribosyltransferase: Permanent activation by engineering of the C-terminus; J.Mol.Biol., 393:464-477, 2009; PubMed: 19683539; DOI: 10.1016/j.jmb.2009.08.019

実験手法

X-RAY DIFFRACTION (2.9 Å)