3G6E

Co-crystal structure of Homoharringtonine bound to the large ribosomal subunit

3G6E の概要

• エントリーDOI: 10.2210/pdb3g6e/pdb
• 関連するPDBエントリー: 3G4S 3G71
• 分子名称: 23S ribosomal RNA, 50S ribosomal protein L11P, 50S ribosomal protein L13P, ... (39 entities in total)
• 機能のキーワード: large ribosomal subunit, antibiotic specificity, homoharringtonine, haloarcula marismortui, ribonucleoprotein, ribosomal protein, rna-binding, rrna-binding, trna-binding, metal-binding, zinc-finger, ribosome
• 由来する生物種: Haloarcula marismortui; 詳細
• 細胞内の位置: Cytoplasm : P12743
• タンパク質・核酸の鎖数: 31
• 化学式量合計: 1461627.50

構造登録者

Gurel, G.,Blaha, G.,Moore, P.B.,Steitz, T.A. (登録日: 2009-02-06, 公開日: 2009-04-28, 最終更新日: 2023-09-06)

• 主引用文献: Gurel, G.,Blaha, G.,Moore, P.B.,Steitz, T.A.; U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome.; J.Mol.Biol., 389:146-156, 2009; PubMed: 19362093; DOI: 10.1016/j.jmb.2009.04.005

実験手法

X-RAY DIFFRACTION (2.7 Å)