3G65

Crystal Structure of the Human Rad9-Rad1-Hus1 DNA Damage Checkpoint Complex

Summary for 3G65

• Entry DOI: 10.2210/pdb3g65/pdb
• Descriptor: Cell cycle checkpoint control protein RAD9A, Cell cycle checkpoint protein RAD1, Checkpoint protein HUS1, ... (4 entities in total)
• Functional Keywords: pcna, dna binding clamp, dna damage, dna repair, exonuclease, hydrolase, nuclease, nucleus, phosphoprotein, cell cycle
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: Q99638 O60671 O60921
• Total number of polymer chains: 3
• Total formula weight: 96038.32

Authors

Dore, A.S.,Kilkenny, M.L.,Rzechorzek, N.J.,Pearl, L.H. (deposition date: 2009-02-06, release date: 2009-05-26, Last modification date: 2023-09-06)

• Primary citation: Dore, A.S.,Kilkenny, M.L.,Rzechorzek, N.J.,Pearl, L.H.; Crystal structure of the rad9-rad1-hus1 DNA damage checkpoint complex--implications for clamp loading and regulation.; Mol.Cell, 34:735-745, 2009; PubMed: 19446481; DOI: 10.1016/j.molcel.2009.04.027

Experimental method

X-RAY DIFFRACTION (2.9 Å)