3G43

Crystal structure of the calmodulin-bound Cav1.2 C-terminal regulatory domain dimer

3G43 の概要

• エントリーDOI: 10.2210/pdb3g43/pdb
• 関連するPDBエントリー: 2F3Y
• 分子名称: Calmodulin, Voltage-dependent L-type calcium channel subunit alpha-1C, CALCIUM ION, ... (4 entities in total)
• 機能のキーワード: calmodulin-bound, coiled coil, calcium channel, acetylation, calcium, methylation, phosphoprotein, polymorphism, ubl conjugation, alternative splicing, brugada syndrome, calcium transport, disease mutation, glycoprotein, ion transport, ionic channel, membrane, transmembrane, transport, voltage-gated channel, metal binding protein
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Membrane ; Multi-pass membrane protein : Q13936
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 86160.31

構造登録者

Fallon, J.L.,Quiocho, F.A. (登録日: 2009-02-03, 公開日: 2009-03-03, 最終更新日: 2024-02-21)

• 主引用文献: Fallon, J.L.,Baker, M.R.,Xiong, L.,Loy, R.E.,Yang, G.,Dirksen, R.T.,Hamilton, S.L.,Quiocho, F.A.; Crystal structure of dimeric cardiac L-type calcium channel regulatory domains bridged by Ca2+{middle dot}calmodulins.; Proc.Natl.Acad.Sci.USA, 106:5135-5140, 2009; PubMed: 19279214; DOI: 10.1073/pnas.0807487106

実験手法

X-RAY DIFFRACTION (2.1 Å)