Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

3G1O

EthR from Mycobacterium tuberculosis in complex with compound BDM14500

Summary for 3G1O
Entry DOI10.2210/pdb3g1o/pdb
Related1U9N 1U9O 3G1L 3G1M
DescriptorTRANSCRIPTIONAL REGULATORY REPRESSOR PROTEIN (TETR-FAMILY) ETHR, tert-butyl 4-(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)piperidine-1-carboxylate (3 entities in total)
Functional Keywordstert family; transcriptional repressor, dna-binding, transcription, transcription regulation
Biological sourceMycobacterium tuberculosis
Total number of polymer chains1
Total formula weight28314.77
Authors
Primary citationWilland, N.,Dirie, B.,Carette, X.,Bifani, P.,Singhal, A.,Desroses, M.,Leroux, F.,Willery, E.,Mathys, V.,Deprez-Poulain, R.,Delcroix, G.,Frenois, F.,Aumercier, M.,Locht, C.,Villeret, V.,Deprez, B.,Baulard, A.R.
Synthetic EthR inhibitors boost antituberculous activity of ethionamide.
NAT.MED. (N.Y.), 15:537-544, 2009
Cited by
PubMed: 19412174
DOI: 10.1038/nm.1950
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.85 Å)
Structure validation

225158

PDB entries from 2024-09-18

PDB statisticsPDBj update infoContact PDBjnumon